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Gene Transfer and the Ethics of First-in-Human Research
monograph
Author(s):
Jonathan Kimmelman
Publication date
(Online):
2009
Publisher:
Cambridge University Press
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Karger: Neurology and Neuroscience
Author and book information
Book
ISBN:
9780511642364
Publication date (Print):
2009
Publication date (Online):
2009
DOI:
10.1017/CBO9780511642364
SO-VID:
deaf9fed-2cd8-45cf-bf05-30d2876afe93
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Book chapters
pp. 1
Introduction: gene transfer lost in translation
pp. 8
What is gene transfer?
pp. 31
Safety, values, and legitimacy: the protean nature of risk in translational trials
pp. 51
Taming uncertainty: risk and gene-transfer clinical research
pp. 72
Succor or suckers? Benefit, risk, and the therapeutic misconception
pp. 89
Looking backward: a model of value for translational trials
pp. 110
The chasm: the ethics of initiating first-in-human clinical trials
pp. 132
Tropic of cancers: gene transfer in resource-poor settings
pp. 153
Great Expectations and Hard Times: expectation management in gene transfer
pp. 178
Something in the sight adjusts itself: conclusions
pp. 192
Epilogue
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