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RNA drug delivery

Articles on key RNA for human medicine, development of pharmaceutical formulation, RNA inhibition and its validation and target influence on human diseases.

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RNA species include messenger RNAs (mRNAs) that are translated into proteins, long non-coding RNAs including transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), and small non-coding RNAs such as micro RNAs (miRNAs) and small interfering RNAs (siRNAs). Exploiting RNA species as therapeutic agents offers new opportunities for drug developers, and the possibility to develop agents against ‘undruggable’ genes and gene products. Furthermore, new screening tools now make it easier to target disease-associated RNA sequences.

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