Modern sequencing and microscopic techniques have expanded our view on nuclear architecture and chromosomal structure. Still, we have only a limited knowledge of the spatial and temporal dynamics of interphase chromosomes. This collection of articles focuses on recent advances in understanding higher order chromatin structure and function.
|Main image credit:|
NIH Image Gallery, Brain Cancer Chromosomes, Flickr, CC BY-NC
|Background image credit:|
Zeiss Microscopy, Cells with nuclei in blue, energy factories in green and the actin cytoskeleton in red, Flickr, CC BY-NC
|ScienceOpen disciplines:||Cell biology, Molecular medicine, Molecular biology, Biophysics, Bioinformatics & Computational biology, Microscopy & Imaging|
|Keywords:||chromatin architecture, chromatin structure, chromatin domain, topologically associating domain, nuclear architecture, genome organization|