This collection provides an overview of important contributions to the subject matter of claudins--from their discovery to the current understanding.
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Erdélyi-Belle Boglárka. Membrane topology of a claudin dimer. The model depicts the conserved structural features of claudins and some of the known interactions and modifications. The domain arrangement of a claudin monomer: TMD1-EL1-TMD2-IL1-TMD3-EL2-TMD4 EL1, EL2 denote the extracellular loops and IL the intracellular loop respectively. The transmembrane domains 1 to 4 (TMD1 to TMD4) and the regions important for hepatitis C virus (HCV) entry and Clostridium perfringens enterotoxin (CPE) binding are shown. Wikimedia Commons. CC BY-SA 4.0. Background extended.
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Mariana Ruiz Villarreal. Cellular tight junction. Diagram showing a tight junction. Tight junctions seal adjacent epithelial cells in a narrow band just beneath their apical surface. Released into the public domain by its author. Original multiplied.