Average rating: | Rated 4.5 of 5. |
Level of importance: | Rated 5 of 5. |
Level of validity: | Rated 4 of 5. |
Level of completeness: | Rated 4 of 5. |
Level of comprehensibility: | Rated 5 of 5. |
Competing interests: | None |
ScienceOpen disciplines: | Immunology, Human biology, Public health, Infectious disease & Microbiology, Microbiology & Virology |
This is an excellent and comprehensive review of the medicinal potential of probiotics. However, the conclusion, in which author states that probiotics might be useful in the prevention of COVID-19 (with this statement I agree), but not in the treatment of COVID-19 (this is something that should be discussed in details), is not sufficiently elaborated, especially when taking into account that some authors have presented the evidence that probiotics might even be useful in the treatment of COVID-19. It might be useful for the author to check my preprint about probiotics and COVID-19, in which useful references about this subject can be found. My preprint is available at https://www.researchgate.net/publication/348540592_Probiotics_and_COVID-19
Second, the heat-killed probiotics are potentially very useful formulation, and it is very good that author mentioned this. Of course, further research on this subject is necessary.
In summary, I think this article is worth publishing, but the conclusion should be sufficiently elaborated.