Review of 'Norovirus: Vaccine Challenges and Development'

Noroviruses are a group of single-stranded RNA pathogens that cause acute gastroenteritis worldwide. Due to the high rates of mutation and evolution in the viruses, creating an effective vaccine to treat norovirus has been difficult. Factors such as the type of vaccine – live attenuated, subunit, or virus like particles – and target age group have limited progress in development. To better understand the best vaccine types and target groups for norovirus vaccine development, continuous research on the subjects will be encouraged. It will be shown that use of virus-like particles (VLPs) and a pediatric target group are the most effective options due to the versatility of VLPs and higher projected norovirus prevention rates for pediatric vaccination. The result of research will be useful to scientists creating norovirus vaccines and will help provide new perspectives for future research.