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      SATB1 is Down-regulated in Clear Cell Renal Cell Carcinoma and Correlates with miR-21-5p Overexpression and Poor Prognosis.

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          Abstract

          Altered expression of special AT-rich sequence binding protein 1 (SATB1) was reported in several types of human cancers. This study aimed to determine the expression levels of SATB1, as well as miR-21-5p -the post-transcriptional repressor of SATB1 expression- in clear cell renal cell carcinoma (ccRCC) and to investigate their association with the progression of ccRCC.

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          Author and article information

          Journal
          Cancer Genomics Proteomics
          Cancer genomics & proteomics
          1790-6245
          1109-6535
          April 24 2016
          : 13
          : 3
          Affiliations
          [1 ] Department of Human Histology and Embryology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland a.kowalczyk@uwm.edu.pl.
          [2 ] Department of Human Histology and Embryology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
          [3 ] Department of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland.
          [4 ] Department of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland Department of Physiotherapy, Wroclaw University School of Physical Education, Wroclaw, Poland.
          [5 ] Department of Human Histology and Embryology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland Department of Histology, Medical University of Gdansk, Gdansk, Poland.
          Article
          13/3/209
          27107063
          197589c4-d5e1-48e2-bce4-994349e1fd7b
          History

          SATB1 expression,IHC,survival,qPCR,clear cell renal cell carcinoma,miR-21-5p,clinicopathological parameters

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