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      Boosting COVID-19 vaccine inoculation and booster shots: a systematic review and meta-analysis of factors that influence Coronavirus vaccine uptake in practice

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          Abstract

          Introduction

          Vaccines alone do not control pandemics, but vaccinations. The hope of COVID-19 pandemic control is hinged on vaccinations and other public health measures. This systematic review/meta-analysis (SR/MA) investigated the factors that inform coronavirus vaccine uptake globally in an attempt to improve COVID-19 immunization.

          Method

          The PRISMA 2020 methodology was used for this review. A total of 2902 articles were identified from electronic databases and other sources. After screening, 33 articles were included in the review and quantitative meta-analysis. Comprehensive meta-analysis software version 3 was used for the meta-analysis.

          Results

          We observed that vaccine effectiveness, side effects and the proportion of acquaintances vaccinated significantly influenced respondents' COVID-19 immunization decision. Also, associations of vaccine effectiveness, smaller risks to serious side effects, free and voluntary vaccinations and fewer vaccine doses, and longer duration to wanning were observed. We also observed variations in vaccine hesitancy trends in studies carried out in Asia, Europe, America, and Africa.

          Conclusion

          Wanning and acquaintance's vaccination status as factors to vaccination are insights the present paper is bringing to the limelight. Health promotion and COVID-19 vaccination planning are crucial for enhancing vaccine uptake.

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          Most cited references32

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          The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

          Matthew J L Page, Joanne E McKenzie, Patrick Bossuyt … (2024)
          The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement replaces the 2009 statement and includes new reporting guidance that reflects advances in methods to identify, select, appraise, and synthesise studies. The structure and presentation of the items have been modified to facilitate implementation. In this article, we present the PRISMA 2020 27-item checklist, an expanded checklist that details reporting recommendations for each item, the PRISMA 2020 abstract checklist, and the revised flow diagrams for original and updated reviews.
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            Historical Origins of the Health Belief Model

            Irwin Rosenstock (1974)
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              COVID-19 Vaccination Hesitancy in the United States: A Rapid National Assessment

              Jagdish Khubchandani, Sushil Sharma, James Price … (2021)
              Given the results from early trials, COVID-19 vaccines will be available by 2021. However, little is known about what Americans think of getting immunized with a COVID-19 vaccine. Thus, the purpose of this study was to conduct a comprehensive and systematic national assessment of COVID-19 vaccine hesitancy in a community-based sample of the American adult population. A multi‐item valid and reliable questionnaire was deployed online via mTurk and social media sites to recruit U.S. adults from the general population. A total of 1878 individuals participated in the study where the majority were: females (52%), Whites (74%), non-Hispanic (81%), married (56%), employed full time (68%), and with a bachelor’s degree or higher (77%). The likelihood of getting a COVID-19 immunization in the study population was: very likely (52%), somewhat likely (27%), not likely (15%), definitely not (7%), with individuals who had lower education, income, or perceived threat of getting infected being more likely to report that they were not likely/definitely not going to get COVID-19 vaccine (i.e., vaccine hesitancy). In unadjusted group comparisons, compared to their counterparts, vaccine hesitancy was higher among African-Americans (34%), Hispanics (29%), those who had children at home (25%), rural dwellers (29%), people in the northeastern U.S. (25%), and those who identified as Republicans (29%). In multiple regression analyses, vaccine hesitancy was predicted significantly by sex, education, employment, income, having children at home, political affiliation, and the perceived threat of getting infected with COVID-19 in the next 1 year. Given the high prevalence of COVID-19 vaccine hesitancy, evidence-based communication, mass media strategies, and policy measures will have to be implemented across the U.S. to convert vaccines into vaccinations and mass immunization with special attention to the groups identified in this study.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Afr Health Sci
                Journal ID (iso-abbrev): Afr Health Sci
                Title: African Health Sciences
                Publisher: Makerere Medical School (Kampala, Uganda )
                ISSN (Print): 1680-6905
                ISSN (Electronic): 1729-0503
                Publication date (Print): June 2023
                Volume: 23
                Issue: 2
                Pages: 3-22
                Affiliations
                [1 ] Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
                [2 ] Public Health and Medicine Research Group, Center for Multidisciplinary Research and Innovation, Jyvaskyla, Finland
                [3 ] Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland
                [4 ] Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Rivers State, Nigeria
                [5 ] Department of Medicine and Therapeutics, Cape Coast Teaching Hospital, Cape Coast, Ghana
                [6 ] Department of Surveying and Geoinformatics, Faculty of Engineering, University of Lagos, Nigeria
                Author notes
                Corresponding author: Frank Adusei-Mensah, Public Health and Medicine Research Group, Center for Multidisciplinary Research and Innovation, Jyvaskyla, Finland. & Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. franka@ 123456uef.fi
                Article
                Publisher ID: jAFHS.v23.i2.pg3
                DOI: 10.4314/ahs.v23i2.3
                PMC ID: 10782355
                PubMed ID: 38223628
                SO-VID: a15bc303-58a6-4d45-a557-4a0c5f010814
                Copyright © © 2023 Adusei-Mensah F et al.
                License:

                Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License ( https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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                Subject: Articles

                Keywords: vaccination,vaccine hesitancy,coronavirus,pandemic,herd immunity,immunization
                Data availability:
                Keywords: vaccination, vaccine hesitancy, coronavirus, pandemic, herd immunity, immunization

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