To determine the accuracy of point-of-care ultrasonography for the diagnosis of pneumonia
in children and young adults by a group of clinicians.
Prospective observational cohort study.
Two urban emergency departments.
Patients from birth to age 21 years undergoing chest radiography for suspected community-acquired
pneumonia.
After documenting clinical examination findings, clinicians with 1 hour of focused
training used ultrasonography to diagnose pneumonia in children and young adults.
Test performance characteristics for the ability of ultrasonography to diagnose pneumonia
were determined using chest radiography as a reference standard. Subgroup analysis
was performed in patients having lung consolidation exceeding 1 cm with sonographic
air bronchograms detected on ultrasonography; specificity and positive likelihood
ratio (LR) were calculated to account for lung consolidation of 1 cm or less with
sonographic air bronchograms undetectable by chest radiography.
Two hundred patients were studied (median age, 3 years; interquartile range, 1-8 years);
56.0% were male, and the prevalence of pneumonia by chest radiography was 18.0%. Ultrasonography
had an overall sensitivity of 86% (95% CI, 71%-94%), specificity of 89% (95% CI, 83%-93%),
positive LR of 7.8 (95% CI, 5.0-12.4), and negative LR of 0.2 (95% CI, 0.1-0.4) for
diagnosing pneumonia by visualizing lung consolidation with sonographic air bronchograms.
In subgroup analysis of 187 patients having lung consolidation exceeding 1 cm, ultrasonography
had a sensitivity of 86% (95% CI, 71%-94%), specificity of 97% (95% CI, 93%-99%),
positive LR of 28.2 (95% CI, 11.8-67.6) and negative LR of 0.1 (95% CI, 0.1-0.3) for
diagnosing pneumonia.
Clinicians are able to diagnose pneumonia in children and young adults using point-of-care
ultrasonography, with high specificity.