Revisión sobre las infecciones no bacterianas del aparato respiratorio: neumonías víricas

Galván, José María; Rajas, Olga; Aspa, Javier

doi:10.1016/j.arbres.2015.02.015

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Revisión sobre las infecciones no bacterianas del aparato respiratorio: neumonías víricas

Author(s): José María Galván, Olga Rajas, Javier Aspa

Publication date: 2015-11-01

Journal: Archivos de bronconeumología

Publisher: Elsevier BV

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.

Theo M. Bestebroer, Albert Osterhaus, Sander van Boheemen … (2012)

A previously unknown coronavirus was isolated from the sputum of a 60-year-old man who presented with acute pneumonia and subsequent renal failure with a fatal outcome in Saudi Arabia. The virus (called HCoV-EMC) replicated readily in cell culture, producing cytopathic effects of rounding, detachment, and syncytium formation. The virus represents a novel betacoronavirus species. The closest known relatives are bat coronaviruses HKU4 and HKU5. Here, the clinical data, virus isolation, and molecular identification are presented. The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.