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      Coronary CTA enhanced with CTA based FFR analysis provides higher diagnostic value than invasive coronary angiography in patients with intermediate coronary stenosis.

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          Abstract

          CTA based FFR, a software based application, enhances diagnostic value of coronary computed tomography angiography (CTA) examination. However it remains unknown whether it improves accuracy over the gold standard of invasive coronary angiography (ICA) in predicting functionally significant coronary stenosis. The aim of our study was to compare diagnostic accuracies of coronary CTA, CTA based FFR, and ICA, with invasive FFR as the reference standard in patients with intermediate stenosis on CTA.

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          Author and article information

          Journal
          J Cardiovasc Comput Tomogr
          Journal of cardiovascular computed tomography
          Elsevier BV
          1876-861X
          1876-861X
          October 13 2018
          : 13
          : 1
          Affiliations
          [1 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: lukas.wardziak@gmail.com.
          [2 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland; Laboratory of Noninvasive Diagnostics of Coronary Artery Disease, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: mkruk@ikard.pl.
          [3 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: weronikapleban@gmail.com.
          [4 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: mdemkow@ikard.pl.
          [5 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: wruzyllo@ikard.pl.
          [6 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: zdzielinska@ikard.pl.
          [7 ] Coronary Artery Disease and Structural Heart Disease Department, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland; Laboratory of Noninvasive Diagnostics of Coronary Artery Disease, Institute of Cardiology, Alpejska 42 St, 04-628, Warsaw, Poland. Electronic address: ckepka@ikard.pl.
          Article
          S1934-5925(18)30407-6
          10.1016/j.jcct.2018.10.004
          30309764
          631c3309-863f-46ce-9697-11d34f637a22
          History

          Coronary artery disease,Invasive coronary angiography,Fractional flow reserve,Computed tomography angiography,Machine learning

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