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The purine path to chemotherapy.

Author(s): G B Elion

Publication date: 1989-04-07

Keywords: Animals, Drug Therapy, Humans, Purines

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Abstract

Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6-mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).