Efficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain: A Systematic Review and Meta-analysis.

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Abstract

Opioid analgesics are commonly used for low back pain, however, to our knowledge there has been no systematic evaluation of the effect of opioid dose and use of enrichment study design on estimates of treatment effect.

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Journal

Journal ID (iso-abbrev): JAMA Intern Med

Title: JAMA internal medicine

Publisher: American Medical Association (AMA)

ISSN (Electronic): 2168-6114

ISSN (Print): 2168-6106

Publication date (Electronic): Jul 01 2016

Volume: 176

Issue: 7

Affiliations

[1 ] The George Institute for Global Health, Sydney, Australia2School of Medicine, Western Sydney University, Penrith, Australia.

[2 ] Musculoskeletal Division, The George Institute for Global Health, Sydney, Australia4Sydney Medical School, University of Sydney, Sydney, Australia.

[3 ] Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.

[4 ] Department of Clinical Pharmacology, St Vincent's Hospital and St Vincent's Clinical School, University of New South Wales, Sydney, Australia7School of Medical Sciences, University of New South Wales, Sydney, Australia.

[5 ] The George Institute for Global Health, Sydney, Australia8Centre for Education and Research on Ageing, Sydney, Australia.

Article

Publisher Item ID: 2522397

DOI: 10.1001/jamainternmed.2016.1251

PubMed ID: 27213267

SO-VID: 8f12e09c-ce9d-450f-9694-9ecb0a67e7f9

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