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Idiopathic Short QT Interval:A New Clinical Syndrome?
Ihor Gussak ,
Pedro Brugada ,
Josep Brugada ,
R. Scott Wright ,
Stephen L. Kopecky ,
Bernard R. Chaitman ,
Preben Bjerregaard
January 1 2001
January 12 2001
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Abstract
In this first clinical report of an idiopathic familial persistently short QT interval
(QTI), we describe three members of one family (a 17-year-old female, her 21-year-old
brother, and their 51-year-old mother) demonstrating this ECG phenomenon, associated
in the 17-year-old with several episodes of paroxysmal atrial fibrillation requiring
electrical cardioversion. Similar ECG changes seen in an unrelated 37-year-old patient
were associated with sudden cardiac death. Our report also describes other manifestations
of abnormal shortening of the QTI and considers the possible arrhythmogenic potential
of the short QTI.