In the field work of population-based research, 3 groups of eyes were graded by 2 observers in LOCS II. The reproducibility of LOCS II was evaluated by agreements (85%-100%) and k values (0.661-1) obtained in our study. The satisfying results show that LOCS II is not only easy to be learned and to be applied consistently by different observers, but also good reproducibility in the field work. The longitudinal cataract study is going to be performed in our plan.