Efficacy of biological agents administered as monotherapy in rheumatoid arthritis: a Bayesian mixed-treatment comparison analysis.

Migliore, Alberto; Bizzi, Emanuele; Egan, Colin Gerard; Bernardi, Mauro; Petrella, Lea

doi:10.2147/TCRM.S89678

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Efficacy of biological agents administered as monotherapy in rheumatoid arthritis: a Bayesian mixed-treatment comparison analysis.

Author(s): Alberto Migliore, Emanuele Bizzi, Colin Gerard Egan, Mauro Bernardi, Lea Petrella

Publication date: 2015

Journal: Therapeutics and Clinical Risk Management

Publisher: Informa UK Ltd.

Keywords: monotherapy, meta-analysis, mixed-treatment comparison, rheumatoid arthritis, biologics, tocilizumab

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Abstract

Biological agents provide an important therapeutic alternative for rheumatoid arthritis patients refractory to conventional disease-modifying antirheumatic drugs. Few head-to-head comparative trials are available.