Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage.

Pinna, Roberto; Campus, Guglielmo; Cumbo, Enzo; Mura, Ida; Milia, Egle

doi:10.2147/TCRM.S70652

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Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage.

Author(s): Roberto Pinna, Guglielmo Campus, Enzo Cumbo, Ida Mura, Egle Milia

Publication date: 2015

Journal: Therapeutics and Clinical Risk Management

Publisher: Dove Medical Press Ltd.

Keywords: radiation-induced xerostomia, salivary gland hypofunction, management strategies

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Abstract

The irradiation of head and neck cancer (HNC) often causes damage to the salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce the patient's quality of life.