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      Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial.

      International Journal of Chronic Obstructive Pulmonary Disease
      Informa UK Ltd.
      HandiHaler, seasonality, TIOSPIR, exacerbations, tiotropium, preventive treatment, Respimat Soft Mist inhaler

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          Abstract

          Although COPD exacerbations are known to occur more frequently in winter, there is little information on hospitalizations and cause-specific mortality. This study aimed to examine seasonal variations in mortality and exacerbations in patients with COPD during the TIOtropium Safety and Performance In Respimat® (TIOSPIR®) trial.

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          Journal
          29497289
          5819585
          10.2147/COPD.S148393

          HandiHaler,seasonality,TIOSPIR,exacerbations,tiotropium,preventive treatment,Respimat Soft Mist inhaler

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