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      Performing Bronchoscopy in Times of the COVID-19 Pandemic: Practice Statement from an International Expert Panel

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          Abstract

          These recommendations for physicians who perform bronchoscopy will help to protect those patients (un)-affected by the current COVID-19 pandemic, minimize the risk of transmission, and maintain clinical care for all patients.

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          Most cited references10

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          Clinical Characteristics of Coronavirus Disease 2019 in China

          Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. Methods We extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use of mechanical ventilation, or death. Results The median age of the patients was 47 years; 41.9% of the patients were female. The primary composite end point occurred in 67 patients (6.1%), including 5.0% who were admitted to the ICU, 2.3% who underwent invasive mechanical ventilation, and 1.4% who died. Only 1.9% of the patients had a history of direct contact with wildlife. Among nonresidents of Wuhan, 72.3% had contact with residents of Wuhan, including 31.3% who had visited the city. The most common symptoms were fever (43.8% on admission and 88.7% during hospitalization) and cough (67.8%). Diarrhea was uncommon (3.8%). The median incubation period was 4 days (interquartile range, 2 to 7). On admission, ground-glass opacity was the most common radiologic finding on chest computed tomography (CT) (56.4%). No radiographic or CT abnormality was found in 157 of 877 patients (17.9%) with nonsevere disease and in 5 of 173 patients (2.9%) with severe disease. Lymphocytopenia was present in 83.2% of the patients on admission. Conclusions During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness. Patients often presented without fever, and many did not have abnormal radiologic findings. (Funded by the National Health Commission of China and others.)
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            Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

            In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patients is limited.
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              Presumed Asymptomatic Carrier Transmission of COVID-19

              This study describes possible transmission of novel coronavirus disease 2019 (COVID-19) from an asymptomatic Wuhan resident to 5 family members in Anyang, a Chinese city in the neighboring province of Hubei.
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                Author and article information

                Journal
                RES
                Respiration
                10.1159/issn.0025-7931
                Respiration
                S. Karger AG
                0025-7931
                1423-0356
                28 April 2020
                :
                :
                : 1-6
                Affiliations
                [_a] aDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China
                [_b] bDepartment of Interventional Pneumology, Ruhrlandklinik, University Medicine Essen, Essen, Germany
                [_c] cDepartment of Respiratory Medicine, Royal Brompton Hospital, London, United Kingdom
                [_d] dNational Heart and Lung Institute, Imperial College, London, United Kingdom
                [_e] eChelsea and Westminster Hospital, London, United Kingdom
                [_f] fRespiratory Department, Santa Creu i Sant Pau Hospital, Barcelona, Spain
                [_g] gDepartment Respiratory Medicine, Royal Melbourne Hospital, Parkville, Victoria, Australia
                [_h] hDepartment Medicine, University of Melbourne, Parkville, Victoria, Australia
                [_i] iDepartment of Biomedical Sciences and Public Health, Polytechnic University of Marche Region Azienda Ospedali Riuniti, Ancona, Italy
                [_j] jDepartment of Respiratory and Critical Care Medicine, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China
                [_k] kDivision of Pulmonary and Critical Care, Mayo Clinic Florida, Jacksonville, Florida, USA
                [_l] lPneumology and Critical Care Medicine, Thoraxklinik University of Heidelberg, Heidelberg, Germany
                [_m] mTranslational Lung Research Center Heidelberg, Heidelberg, Germany
                Author notes
                *Prof. Luo Fengming, Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041 (China), luofengming@hotmail.com
                Author information
                https://orcid.org/0000-0003-0681-1325
                https://orcid.org/0000-0002-9052-4638
                Article
                507898 Respiration
                10.1159/000507898
                32344422
                d9a6a90c-a63f-431b-a7a2-ebb22ca81450
                © 2020 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                : 14 April 2020
                : 14 April 2020
                Page count
                Figures: 3, Tables: 1, Pages: 6
                Categories
                Interventional Pulmonology

                Internal medicine,Respiratory medicine,Clinical Psychology & Psychiatry,Microbiology & Virology,Infectious disease & Microbiology
                COVID-19,Interventional pneumology,Bronchoscopy

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