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      Lelystad virus, the cause of porcine epidemic abortion and respiratory syndrome: a review of mystery swine disease research at Lelystad.

      Veterinary Microbiology
      Abortion, Veterinary, microbiology, Animals, Cell Line, Cells, Cultured, Chick Embryo, Female, Pregnancy, RNA Viruses, classification, isolation & purification, physiology, Respiratory Tract Infections, veterinary, Swine, Swine Diseases, Virus Diseases

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          Abstract

          This paper reviews the laboratory investigations that led us to isolate the Lelystad virus and demonstrate that this virus causes mystery swine disease. We describe: 1) isolating the virus from the disease; 2) characterizing the virus as a new enveloped RNA virus; 3) reproducing the disease experimentally with the isolated Lelystad virus; 4) isolating the virus from the experimentally induced disease.

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