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      Kimura's disease and membranous nephropathy.

      Nephron. Physiology
      Aged, Angiolymphoid Hyperplasia with Eosinophilia, complications, etiology, pathology, Candida albicans, immunology, Glomerulonephritis, Membranous, Humans, Hypersensitivity, Immediate, Male

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          Abstract

          An interesting association of Kimura's disease and membranous nephropathy is reported in a 71-year-old Chinese patient, 40 years after emigrating to the UK from Hong Kong. Significant blood eosinophilia and a very high serum IgE level were detected, the latter with a moderate level of specificity to Candida albicans. Light microscopy of renal biopsy was unremarkable despite a proteinuria of nephrotic proportions; diffuse subepithelial dense deposits compatible with membranous nephropathy were identified on electron microscopy. The atopic nature of Kimura's disease is confirmed and C. albicans is suggested as a possible causative agent.

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