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      Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology.

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          Abstract

          A rising prevalence of end-stage renal disease (ESRD) has led to a rise in ESRD-related pericardial syndromes, calling for a better understanding of its pathophysiology, diagnoses, and management. Uremic pericarditis, the most common manifestation of uremic pericardial disease, is a contemporary problem that calls for intensive hemodialysis, anti-inflammatories, and often, drainage of large inflammatory pericardial effusions. Likewise, asymptomatic pericardial effusions can become large and impact the hemodynamics of patients on chronic hemodialysis. Constrictive pericarditis is also well documented in this population, ultimately resulting in pericardiectomy for definitive treatment. The management of pericardial diseases in ESRD patients involves internists, cardiologists, and nephrologists. Current guidelines lack clarity with respect to the management of pericardial processes in the ESRD population. Our review aims to describe the etiology, classification, clinical manifestations, diagnostic imaging tools, and treatment options of pericardial diseases in this population.

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          Author and article information

          Journal
          Clin Cardiol
          Clinical cardiology
          Wiley
          1932-8737
          0160-9289
          Oct 2017
          : 40
          : 10
          Affiliations
          [1 ] Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio.
          [2 ] Department of Cardiovascular Medicine, Center for Diagnosis and Treatment of Pericardial Diseases, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
          [3 ] Department of Nephrology and Urology, Cleveland Clinic, Cleveland, Ohio.
          Article
          10.1002/clc.22770
          28873222
          c33dc365-bfa6-4c5b-9458-838fae898057
          History

          Constrictive Pericarditis,End-Stage,Pericardial Effusion,Renal Disease,Uremic Pericarditis

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