The presence of IgG antibodies against Helicobacter pylori in haemodialysis patients was studied. Furthermore the presence of antibodies in different age cohorts was compared with a population of patients suffering from non-ulcer dyspepsia and healthy blood donors. Antibodies were present in 43% of the haemodialysis patients. In the younger age groups the presence was low compared with the control populations; this difference was not present in the older age cohorts. There was an increasing prevalence of antibodies with rising age. We did not find a correlation between the height of the blood urea levels, before and after haemodialysis, and the presence of antibodies against H. pylori. In conclusion, a high blood urea level does not seem to be a risk factor, per se, for acquiring H. pylori, and the presence of the microorganism probably does not contribute, to a large extent, to the frequent dyspeptic complaints in haemodialysis patients.