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The safety of liposome bupivacaine following various routes of administration in animals.

Author(s): Girish P Joshi, Gary Patou, Vladimir Kharitonov

Publication date: 2015

Journal: Journal of Pain Research

Publisher: Informa UK Ltd.

Keywords: spinal injections, local anesthesia, bupivacaine, drug administration routes

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Abstract

This report presents results from four preclinical studies evaluating safety and pharmacokinetics (PKs) of liposome bupivacaine following intravascular (intravenous [IV], intra-arterial [IA]), epidural, and intrathecal administration in dogs.

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PubMed ID:: 26586964

PMC ID:: 4634838

DOI:: 10.2147/JPR.S85424

Keywords: spinal injections,local anesthesia,bupivacaine,drug administration routes

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Keywords: spinal injections, local anesthesia, bupivacaine, drug administration routes

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