Comparative in vivo lung delivery of hydrofluoroalkane-salbutamol formulation via metered-dose inhaler alone, with plastic spacer, or with cardboard tube.
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Abstract
To compare the lung delivery of chlorofluorocarbon-free salbutamol via a pressurized
metered-dose inhaler (pMDI) alone, a pMDI with a small-volume plastic spacer, and
a pMDI with a cardboard tube.
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Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics,
Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK.