36
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis.

      Read this article at

      ScienceOpenPublisherPubMed
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Gastro-oesophageal reflux symptoms are common in the community, but there has been no definitive systematic review and meta-analysis of data from all studies to estimate their global prevalence, or potential risk factors for them.

          Related collections

          Most cited references102

          • Record: found
          • Abstract: found
          • Article: not found

          Epidemiology of gastro-oesophageal reflux disease: a systematic review.

          A systematic review of the epidemiology of gastro-oesophageal reflux disease (GORD) has been performed, applying strict criteria for quality of studies and the disease definition used. The prevalence and incidence of GORD was estimated from 15 studies which defined GORD as at least weekly heartburn and/or acid regurgitation and met criteria concerning sample size, response rate, and recall period. Data on factors associated with GORD were also evaluated. An approximate prevalence of 10-20% was identified for GORD, defined by at least weekly heartburn and/or acid regurgitation in the Western world while in Asia this was lower, at less than 5%. The incidence in the Western world was approximately 5 per 1000 person years. A number of potential risk factors (for example, an immediate family history and obesity) and comorbidities (for example, respiratory diseases and chest pain) associated with GORD were identified. Data reported in this systematic review can be interpreted with confidence as reflecting the epidemiology of "true" GORD. The disease is more common in the Western world than in Asia, and the low rate of incidence relative to prevalence reflects its chronicity. The small number of studies eligible for inclusion in this review highlights the need for global consensus on a symptom based definition of GORD.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The burden of selected digestive diseases in the United States.

            Gastrointestinal (GI) and liver diseases inflict a heavy economic burden. Although the burden is considerable, current and accessible information on the prevalence, morbidity, and cost is sparse. This study was undertaken to estimate the economic burden of GI and liver disease in the United States for use by policy makers, health care providers, and the public. Data were extracted from a number of publicly available and proprietary national databases to determine the prevalence, direct costs, and indirect costs for 17 selected GI and liver diseases. Indirect cost calculations were purposefully very conservative. These costs were compared with National Institutes of Health (NIH) research expenditures for selected GI and liver diseases. The most prevalent diseases were non-food-borne gastroenteritis (135 million cases/year), food-borne illness (76 million), gastroesophageal reflux disease (GERD; 19 million), and irritable bowel syndrome (IBS; 15 million). The disease with the highest annual direct costs in the United States was GERD ($9.3 billion), followed by gallbladder disease ($5.8 billion), colorectal cancer ($4.8 billion), and peptic ulcer disease ($3.1 billion). The estimated direct costs for these 17 diseases in 1998 dollars were $36.0 billion, with estimated indirect costs of $22.8 billion. The estimated direct costs for all digestive diseases were $85.5 billion. Total NIH research expenditures were $676 million in 2000. GI and liver diseases exact heavy economic and social costs in the United States. Understanding the prevalence and costs of these diseases is important to help set priorities to reduce the burden of illness.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              U. S. Householder survey of functional gastrointestinal disorders

                Bookmark

                Author and article information

                Journal
                Gut
                Gut
                BMJ
                1468-3288
                0017-5749
                Feb 23 2017
                Affiliations
                [1 ] Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
                [2 ] The Royal Free Hospital and University College London Institute for Liver and Digestive Health, London, UK.
                [3 ] Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.
                [4 ] Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK.
                [5 ] Division of Gastroenterology, Health Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
                [6 ] Iran University of Medical Sciences, Tehran, Iran.
                [7 ] The University of Nottingham, Nottingham, UK.
                Article
                gutjnl-2016-313589
                10.1136/gutjnl-2016-313589
                28232473
                f995e6a1-6084-4ef2-8287-bad7fc6311a5
                History

                GASTROESOPHAGEAL REFLUX DISEASE,META-ANALYSIS
                GASTROESOPHAGEAL REFLUX DISEASE, META-ANALYSIS

                Comments

                Comment on this article