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      Immunology and disease control: a systems approach.

      IEEE transactions on bio-medical engineering

      Acute Disease, Chronic Disease, Communicable Diseases, immunology, therapy, Computer Simulation, Humans, Influenza, Human, Models, Biological, Systems Theory

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          Abstract

          The application of system theory (or more precisely, differential equations) to immunology and disease, in general, is presented here. Particular results from U.S.-Russian research collaboration depict the potential role of such systematic analysis for more effective health care and disease control. In particular, some emphasis is given to control of influenza. After a brief systematic overview of immunology, a simple infectious disease model is developed to explain four basic forms of disease: subclinical, acute, lethal and chronic. Then, disease treatment is studied.

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          Journal
          7959801
          10.1109/10.324526

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