24
views
0
recommends
+1 Recommend
2 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Ophthalmic signs and complications of the COVID-19 infection

      1 , 2 , * ,
      Developments in Health Sciences
      Akadémiai Kiadó
      Coronavirus-19, pandemic, ophthalmology, ophthalmic complications

      Read this article at

      ScienceOpenPublisher
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Coronavirus-19 infection caused a mysterious pandemic worldwide. Some people experienced flu-like symptoms, while others have died due to pulmonary complications. Besides droplet spread, other routes of infection started to be suspected, such as through eye contact. During the first phase of the pandemic, pulmonary symptoms were in focus, later other signs and symptoms were also published. Eyelid, anterior and posterior segment symptoms, neuro-ophthalmic complications, and orbital problems related to COVID-19 infections are discussed in this article. It is important to detect the serious signs and symptoms to prevent late, sight threatening complications of COVID-19 infection.

          Related collections

          Most cited references25

          • Record: found
          • Abstract: found
          • Article: not found

          Miller Fisher Syndrome and polyneuritis cranialis in COVID-19

          To report two patients infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) who acutely presented with Miller Fisher syndrome and polyneuritis cranialis, respectively. Patient data were obtained from medical records from the University Hospital “Príncipe de Asturias”, Alcalá de Henares, Madrid, Spain and from the University Hospital “12 de Octubre”, Madrid, Spain. The first patient was a 50-year-old man who presented with anosmia, ageusia, right internuclear ophthalmoparesis, right fascicular oculomotor palsy, ataxia, areflexia, albuminocytologic dissociation and positive testing for GD1b-IgG antibodies. Five days before, he had developed a cough, malaise, headache, low back pain, and a fever. The second patient was a 39-year-old man who presented with ageusia, bilateral abducens palsy, areflexia and albuminocytologic dissociation. Three days before, he had developed diarrhea, a low-grade fever, and a poor general condition. The oropharyngeal swab test for coronavirus disease 2019 (COVID-19) by qualitative real-time reverse-transcriptase–polymerase-chain-reaction assay was positive in both patients and negative in the cerebrospinal fluid. The first patient was treated with intravenous immunoglobulin and the second, with acetaminophen. Two weeks later, both patients made a complete neurological recovery, except for residual anosmia and ageusia in the first case. Our two cases highlight the rare occurrence of Miller Fisher syndrome and polyneuritis cranialis during the COVID-2 pandemic. Neurological manifestations may occur because of an aberrant immune response to COVID-19. The full clinical spectrum of neurological symptoms in patients with COVID-19 remains to be characterized.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The evidence of SARS-CoV-2 infection on ocular surface

            This is a cross-sectional study of patients who received a COVID-19 diagnosis between December 30, 2019 and February 7, 2020 at Tongji Hospital. A total of 102 patients (48 Male [47%] and 54 Female [53%]) with clinical symptoms, Rt, and chest Computed Tomography (CT) abnormalities were identified with a clinical diagnosis of COVID-19. Patients had a mean [SD] gestational age of 57.63 [14.90] years. Of a total of 102 patients identified, 72 patients (36 men [50%] and 36 women [50%]; mean [SD] age, 58.68 [14.81] years) were confirmed to have COVID-19 by laboratory diagnosis with a SARS-CoV-2 RT-PCR assay. Only two patients (2.78%) with conjunctivitis were identified from 72 patients with a laboratory confirmed COVID-19. Of those two patients, SARS-CoV-2 RNA fragments were found in ocular discharges by SARS-CoV-2 RT-PCR in only one patient. Our findings suspect the incidence of SARS-CoV-2 infection through the ocular surface is extremely low, while the nosocomial infection of SARS-CoV-2 through the eyes after occupational exposure is a potential route. To lower the SARS-CoV-2 nosocomial infection, all health care professionals should wear protective goggles. The inefficient diagnostic method and the sampling time lag may contribute to the lower positive rate of conjunctival swab samples of SARS-CoV-2.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Mucormycosis with orbital compartment syndrome in a patient with COVID-19

              Abstract During the current pandemic of COVID-19, a myriad of manifestations and complications has emerged and are being reported on. We are discovering patients with COVID-19 are at increased risk of acute cardiac injury, arrythmias, thromboembolic complications (pulmonary embolism and acute stroke), and secondary infection to name a few. I describe a novel case of COVID-19 in a previously healthy 33-year-old female who presented for altered mental status and proptosis. She was ultimately diagnosed with mucormycosis and orbital compartment syndrome, in addition to COVID-19. Early identification of these high morbidity conditions is key to allow for optimal treatment and improved outcomes.
                Bookmark

                Author and article information

                Contributors
                Journal
                2066
                Developments in Health Sciences
                DHS
                Akadémiai Kiadó (Budapest )
                2630-9378
                2630-936X
                30 July 2021
                16 July 2021
                : 3
                : 4
                : 79-82
                Affiliations
                [1 ] Department of Ophthalmology, Faculty of Medicine, Semmelweis University , Budapest, Hungary
                [2 ] Department of Clinical Ophthalmology, Faculty of Health Sciences, Semmelweis University , Budapest, Hungary
                Author notes
                [* ]Corresponding author. E-mail: zoltan.nagy100@ 123456gmail.com
                Author information
                https://orcid.org/0000-0002-7330-0464
                Article
                10.1556/2066.2021.40001
                f3012d6b-b365-4f9e-b550-fdb68bdbfebb
                © 2021 The Author(s)

                Open Access. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changes – if any – are indicated.

                History
                Page count
                Equations: 0, References: 25, Pages: 04

                Medicine,Immunology,Health & Social care,Microbiology & Virology,Infectious disease & Microbiology
                ophthalmic complications,ophthalmology,pandemic,Coronavirus-19

                Comments

                Comment on this article