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      Limitations of creatinine as a filtration marker in glomerulopathic patients

      Kidney International

      Springer Nature

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          Most cited references 7

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          Determination of Dextran with Anthrone

           T Scott,  E. H. Melvin (1953)
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            Determination of serum creatinine by a direct colorimetric method.

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              A simple method of estimating progression of chronic renal failure.

              In 31 of 34 patients with chronic renal insufficiency caused by various diseaes, reciprocal serum-creatinine concentration declined linearly as creatinine concentration rose from a mean of 2-6 mg/dl to 14-8 mg/dl over an average of 71 months. These results indicate that in most cases reciprocal serum-creatinine declines linearly with time as chronic renal failure progresses. Analysis of this relation in individual patients gives an estimate of the progression of the disease, may help to determine the effects of therapy, and could be used to predict when dialysis will become necessary.
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                Author and article information

                Journal
                10.1038/ki.1985.205

                http://www.elsevier.com/tdm/userlicense/1.0/

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