Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.

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Abstract

New drug treatments, clinical trials, and standards of quality for assessment of evidence justify an update of evidence-based recommendations for the pharmacological treatment of neuropathic pain. Using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE), we revised the Special Interest Group on Neuropathic Pain (NeuPSIG) recommendations for the pharmacotherapy of neuropathic pain based on the results of a systematic review and meta-analysis.

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Journal

Journal ID (iso-abbrev): Lancet Neurol

Title: The Lancet. Neurology

ISSN (Electronic): 1474-4465

ISSN (Print): 1474-4422

Publication date (Electronic): Feb 2015

Volume: 14

Issue: 2

Affiliations

[1 ] Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

[2 ] INSERM U-987, Centre d'Evaluation et de Traitement de la Douleur, Hôpital Ambroise Paré, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, France; Université Versailles Saint-Quentin, France. Electronic address: nadine.attal@apr.aphp.fr.

[3 ] Division of Clinical and Translational Research, Department of Anesthesiology, Washington University School of Medicine, St Louis, MO, USA.

[4 ] Departments of Anesthesiology and Pharmacy, Tufts Medical Center, Boston, MA, USA.

[5 ] Division of Neurological Pain Research and Therapy, Department of Neurology, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany.

[6 ] Department of Anesthesiology and Department of Neurology, Center for Human Experimental Therapeutics, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

[7 ] Department of Anesthesiology and Perioperative Medicine and Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.

[8 ] Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland; Mutual Insurance Company Etera, Helsinki, Finland.

[9 ] Department of Pain Management and Research, Oslo University Hospital, Oslo, Norway; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

[10 ] Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.

[11 ] Brain Function Research Group, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, South Africa.

[12 ] Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, Pain Research, Churchill Hospital, Oxford, UK.

[13 ] Johns Hopkins School of Medicine, Division of Pain Medicine, Department of Anesthesiology and Critical Care Medicine, Baltimore, MD, USA.

[14 ] Pain Research, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK; Pain Medicine, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.

[15 ] California Pacific Medical Center Research Institute and UCSF Pain Management Center, San Francisco, CA, USA.

[16 ] Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia.

[17 ] Department of Pain Management, Greenwich Hospital, HammondCare, Sydney, NSW, Australia; Kolling Institute, Sydney Medical School-Northern, University of Sydney, Sydney, NSW, Australia.

[18 ] Division of Population Health Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland.

[19 ] Division of Pain Medicine, Department of Anesthesiology, UCSD, San Diego, CA, USA.

Article

Publisher Item ID: S1474-4422(14)70251-0 Mid ID: NIHMS702730

DOI: 10.1016/S1474-4422(14)70251-0

PubMed ID: 25575710

SO-VID: 234edac7-7174-4db8-9d78-c8104e44ec9c

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