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      Efficacy and safety of rivaroxaban in patients with diabetes and nonvalvular atrial fibrillation: the Rivaroxaban Once-daily, Oral, Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF Trial).

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          Abstract

          The prevalence of both atrial fibrillation (AF) and diabetes mellitus (DM) are rising, and these conditions often occur together. Also, DM is an independent risk factor for stroke in patients with AF. We aimed to examine the safety and efficacy of rivaroxaban vs warfarin in patients with nonvalvular AF and DM in a prespecified secondary analysis of the ROCKET AF trial.

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          Author and article information

          Journal
          Am. Heart J.
          American heart journal
          Elsevier BV
          1097-6744
          0002-8703
          Oct 2015
          : 170
          : 4
          Affiliations
          [1 ] Icahn School of Medicine at Mount Sinai, New York, NY.
          [2 ] Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: jonathan.halperin@mssm.edu.
          [3 ] Duke Clinical Research Institute, Duke University Medical Center, Durham, NC.
          [4 ] University of Cincinnati College of Medicine, Cincinnati, OH.
          [5 ] Department of Cardiovascular Medicine, Division of Electrophysiology, University Hospital Münster, Münster, Germany.
          [6 ] Ruprecht-Karls University, Heidelberg, Germany.
          [7 ] School of Medicine and Pharmacology, University of Western Australia, Crawley, Australia.
          [8 ] Janssen Research & Development, Raritan, NJ.
          [9 ] Massachusetts General Hospital and Harvard Medical School, Boston, MA.
          [10 ] Bayer HealthCare Pharmaceuticals, Whippany, NJ.
          [11 ] Department of Medicine, Stanford University, Stanford, CA.
          [12 ] University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
          Article
          S0002-8703(15)00443-3
          10.1016/j.ahj.2015.07.006
          26386791
          e086b32d-e62a-4ed3-98e0-a6258248358d
          History

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