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      Insulinemia and blood pressure responses to oral glucose load in primary hypertensive patients.

      1 , ,
      Cardiology

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          Abstract

          Fourteen hypertensive patients and 14 normotensive control subjects were submitted to the oral glucose test and their plasma potassium, glucose and insulin levels were measured. Cardiovascular responses were evaluated by blood pressure and pulse rate measurements. Five of 14 hypertensive patients were hyperinsulinemic and had higher blood glucose levels, suggesting insulin resistance. Systolic blood pressure, heart rate and double product increased significantly in normotensive subjects and slightly in hyperinsulinemic patients, but not in normoinsulinemic hypertensive patients. These results seem to indicate the presence of insulin resistance in a particular group of primary hypertensive patients and a smaller cardiovascular response after glucose overload.

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          Author and article information

          Journal
          Cardiology
          Cardiology
          0008-6312
          0008-6312
          1991
          : 79
          : 1
          Affiliations
          [1 ] Department of Internal Medicine, School of Medicine, Campinas State University, São Paulo, Brazil.
          Article
          1777910
          c9ccd484-0b63-46c1-9a10-1af060936107
          History

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