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      Call for Papers: Green Renal Replacement Therapy: Caring for the Environment

      Submit here before July 31, 2024

      About Blood Purification: 3.0 Impact Factor I 5.6 CiteScore I 0.83 Scimago Journal & Country Rank (SJR)

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      The drumbeat of renal failure: symbiosis of prevention and renal replacement therapy.

      Blood purification
      Developing Countries, Diabetes Mellitus, Type 2, complications, epidemiology, prevention & control, therapy, Diabetic Nephropathies, Health Services Accessibility, statistics & numerical data, Humans, Hypertension, Kidney Failure, Chronic, etiology, Renal Replacement Therapy

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          Abstract

          The global population of patients with end-stage renal disease is rising rapidly, especially in developing countries. The possibility and economic burden of renal replacement therapy will be greatly challenged in the next decade as the prevalence of diabetes and hypertension rises. The establishment of effective prevention and intervention measures creates a means by which the increasing burden of renal replacement therapy can be reduced. Copyright 2004 S. Karger AG, Basel

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          Progression, remission, regression of chronic renal diseases.

          The prevalence of chronic renal disease is increasing worldwide. Most chronic nephropathies lack a specific treatment and progress relentlessly to end-stage renal disease. However, research in animals and people has helped our understanding of the mechanisms of this progression and has indicated possible preventive methods. The notion of renoprotection is developing into a combined approach to renal diseases, the main measures being pharmacological control of blood pressure and reduction of proteinuria. Lowering of blood lipids, smoking cessation, and tight glucose control for diabetes also form part of the multimodal protocol for management of renal patients. With available treatments, dialysis can be postponed for many patients with chronic nephropathies, but the real goal has to be less dialysis-in other words remission of disease and regression of structural damage to the kidney. Experimental and clinical data lend support to the notion that less dialysis (and maybe none for some patients) is at least possible.
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            Maps of end-stage renal disease and amounts of angiotensin-converting enzyme inhibitors prescribed in Japan.

            We recently found regional differences in the incidence of end-stage renal disease (ESRD) in Japan, which is generally ethnically homogeneous, suggesting that factors other than genetic may contribute to the difference. Here, we examined regional differences in the amounts of expenses spent on antihypertensives, especially angiotensin-converting enzyme (ACE) inhibitors, in our search for an explanation.
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