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      Evidence-based practice recommendations for nutrition-related management of children and adults with cystic fibrosis and pancreatic insufficiency: results of a systematic review.

      Journal of the American Dietetic Association

      Weight Gain, Adolescent, Practice Guidelines as Topic, enzymology, Pancreas, Nutritional Status, physiology, Nutritional Physiological Phenomena, Male, Humans, Growth, Female, diet therapy, Exocrine Pancreatic Insufficiency, Evidence-Based Medicine, therapeutic use, administration & dosage, Enzymes, Energy Intake, Cystic Fibrosis, Child Nutritional Physiological Phenomena, Child, Adult

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          Abstract

          The Cystic Fibrosis Foundation established a process of systematic review of evidence to inform the development of clinical care guidelines and encourage evidence-based practice. The Subcommittee on Growth and Nutrition reviewed the evidence in two areas: energy intake and dosing for pancreatic enzyme replacement therapy. Evidence-based recommendations are presented here. Also, an ad hoc working group conducted a review of the literature and performed new analyses using the Cystic Fibrosis Foundation Patient Registry to update the recommendations for growth and weight-status monitoring. These Registry data-based recommendations are presented.

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          Journal
          10.1016/j.jada.2008.02.020
          18442507

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