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      Echocardiographic evaluation of left-ventricular diastolic function in patients with chronic pulmonary hypertension.

      1 , , , ,

      Cardiology

      S. Karger AG

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          Abstract

          Different patterns of left-ventricular (LV) diastolic dysfunction were reported in patients with pulmonary hypertension (PHT). There are no data regarding the relationship between the severity of PHT and LV diastolic dysfunction. In order to determine the severity of PHT at which LV diastolic dysfunction occurs and to identify its pattern, we studied by Doppler echocardiography 120 patients with PHT (57 with severe PHT and 63 with mild or moderate PHT) and compared them with 75 normal controls. Systolic pulmonary artery pressure (SPAP) was measured by tricuspid regurgitant jet method and the usual transmitral LV diastolic indices were recorded. LV diastolic dysfunction of impaired relaxation type is most commonly seen in patients with severe PHT. No differences were observed between patients with mild and moderate PHT regarding LV diastolic function. A SPAP > or =60 mm Hg is needed to induce changes in the LV diastolic filling pattern.

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          Author and article information

          Journal
          Cardiology
          Cardiology
          S. Karger AG
          0008-6312
          0008-6312
          2001
          : 95
          : 2
          Affiliations
          [1 ] Echocardiography Laboratory, Division of Cardiology, Department of Internal Medicine, University of Texas Medical School at Houston and Memorial Hermann Hospital, Houston 77030, USA.
          Article
          47353
          10.1159/000047353
          11423714
          22c4388c-5ce8-48e4-afdf-97aa22a459e6

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