The aim of the present study is to present a model of depressive vulnerability centered on anhedonia. After a review of the literature, we suggest a specific symptomatic profile associating anhedonia, introversion, low sensation-seeking, autonomy, dysfunctional attitudes, high displeasure capacity, obsessive-compulsive features, passitivity and pessimism. This symptomatic profile could constitute a mild chronic mood disorder which, following stress, might decompensate into unipolar endogenomorphic depression. Several methods of research are suggested to test the validity of our model.