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Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients
brief-report
Dustin R Long , MD
1 ,
Saurabh Gombar , MD, PhD
2 ,
Catherine A Hogan , MD, MSc
2
,
3 ,
Alexander L Greninger , MD, PhD
4
,
5 ,
Vikas O’Reilly Shah , MD, PhD
6 ,
Chloe Bryson-Cahn , MD
7 ,
Bryan Stevens , MD
2
,
3 ,
Arjun Rustagi , MD, PhD
8 ,
Keith R Jerome , MD, PhD
4
,
5 ,
Christina S Kong , MD
2 ,
James Zehnder , MD
2 ,
Nigam H Shah , MD, PhD
9 ,
Noel S Weiss , MD, DrPH
10 ,
Benjamin A Pinsky , MD, PhD
2
,
3
,
8 ,
Jacob Sunshine , MD, MSc
6
07 June 2020
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Abstract
Using data for 20,912 patients from two large academic health systems, we analyzed the frequency of SARS-CoV-2 RT-PCR test-discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and similar across institutions.