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      Ultrastructure of canine vasoformative tumors.

      Journal of Vascular Research
      Animals, Cell Nucleolus, ultrastructure, Cell Nucleus, Cytoplasm, Dog Diseases, pathology, Dogs, Endothelium, Vascular, Hemangiopericytoma, veterinary, Hemangiosarcoma, Humans, Intercellular Junctions, Intermediate Filaments, Microscopy, Electron

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          Abstract

          The transmission electron microscope was used to examine 20 spontaneous canine hemangiosarcomas or hemangiopericytomas in order to define their fine ultrastructural features, and to compare those features with descriptions of human counterpart neoplasms. From specimen to specimen the neoplasms examined showed considerable structural heterogeneity but, in composite, appeared similar to the prototype human tumors. These data suggest that the canine hemangiosarcoma and hemangiopericytoma might serve as comparative models for studies of the morphogenesis of vasoformative neoplasms.

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