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Primary or secondary antifungal prophylaxis in patients with hematological maligancies: efficacy and damage.

Author(s): Habip Gedik, Funda Simşek, Taner Yıldırmak, Arzu Kantürk, Deniz Arıca, Demet Aydın, Naciye Demirel, Osman Yokuş

Publication date: 2014

Journal: Therapeutics and Clinical Risk Management

Publisher: Informa UK Ltd.

Keywords: primary antifungal prophylaxis, invasive fungal infection, hematological malignancy, secondary antifungal prophylaxis, azole resistance, febrile neutropenia

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Abstract

Patients with hematological malignancies often develop febrile neutropenia (FN) as a complication of cancer chemotherapy. Primary or secondary antifungal prophylaxis is recommended for patients with hematological malignancies to reduce the risk of invasive fungal infection (IFI). This study retrospectively evaluated the efficacy and potential harm of administration of primary and secondary antifungal prophylaxis to patients with hematological malignancies at one hospital.

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PubMed ID:: 24855365

PMC ID:: 4011927

DOI:: 10.2147/TCRM.S59683

Keywords: primary antifungal prophylaxis,invasive fungal infection,hematological malignancy,secondary antifungal prophylaxis,azole resistance,febrile neutropenia

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Keywords: primary antifungal prophylaxis, invasive fungal infection, hematological malignancy, secondary antifungal prophylaxis, azole resistance, febrile neutropenia

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