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      Liberal versus conservative fluid therapy in adults and children with sepsis or septic shock.

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          Abstract

          Sepsis and septic shock are potentially life-threatening complications of infection that are associated with high morbidity and mortality in adults and children. Fluid therapy is regarded as a crucial intervention during initial treatment of sepsis. Whether conservative or liberal fluid therapy can improve clinical outcomes in patients with sepsis and septic shock remains unclear.

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          Author and article information

          Journal
          Cochrane Database Syst Rev
          The Cochrane database of systematic reviews
          Wiley
          1469-493X
          1361-6137
          Dec 10 2018
          : 12
          Affiliations
          [1 ] Intensive Care Unit, Second Affiliated Hospital Medical College, Zhejiang University, 88 Jiefang Road, Hangzhou, China, 310009.
          Article
          10.1002/14651858.CD010593.pub2
          6517253
          30536956

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