Liberal versus conservative fluid therapy in adults and children with sepsis or septic shock.

Abstract

Sepsis and septic shock are potentially life-threatening complications of infection that are associated with high morbidity and mortality in adults and children. Fluid therapy is regarded as a crucial intervention during initial treatment of sepsis. Whether conservative or liberal fluid therapy can improve clinical outcomes in patients with sepsis and septic shock remains unclear.

Journal

Journal ID (iso-abbrev): Cochrane Database Syst Rev

Title: The Cochrane database of systematic reviews

Publisher: Wiley

ISSN (Electronic): 1469-493X

ISSN (Print): 1361-6137

Publication date (Electronic): Dec 10 2018

Volume: 12

Affiliations

[1 ] Intensive Care Unit, Second Affiliated Hospital Medical College, Zhejiang University, 88 Jiefang Road, Hangzhou, China, 310009.

Article

DOI: 10.1002/14651858.CD010593.pub2

PMC ID: 6517253

PubMed ID: 30536956