92
views
0
recommends
+1 Recommend
1 collections
    2
    shares
      • Record: found
      • Abstract: found
      • Article: found

      New octadecanoid derivatives from the seeds of Ipomoea nil

      , , , ,
      Chinese Journal of Natural Medicines
      Elsevier BV

      Read this article at

      ScienceOpenPublisher
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Four new octadecanoid derivatives ( 1 - 4 ) including a pair of enantiomers ( 1 / 2 ), along with 12 known analogues ( 5 - 16 ), were isolated from the seeds of Ipomoea nil. Their structures were determined by detailed spectroscopic analyses and comparison with reported data of structurally related compounds, with the absolute configurations of 1 and 2 being assigned by an in situ dimolybdenum ECD method. Our bioassays revealed that these isolates did not show ABTS radical scavenging activity while 10 and 13 displayed better α -glucosidase inhibitory activity than the positive control acarbose (IC 50 167.7 ± 1.55 μmol-L −1 ), with IC 50 of 92.73 ± 3.12 and 11.39 ± 2.18 μmol-L −1 , respectively.

          Author and article information

          Journal
          Chinese Journal of Natural Medicines
          Chinese Journal of Natural Medicines
          Elsevier BV
          18755364
          April 2019
          April 2019
          : 17
          : 4
          : 303-307
          Article
          10.1016/S1875-5364(19)30034-2
          be670f7a-9d93-476b-a708-be9e939a3abc
          © 2019

          https://www.elsevier.com/tdm/userlicense/1.0/

          History

          Comments

          Comment on this article