Abstract: The present note reports the first record of Vampyrodes caraccioli in the Brazilian state of Amazonas, and the central Amazon region, based on 44 specimens caught in the Auati-Paraná Extractive Reserve, north bank of the Solimões/Amazonas River. Our record fills a distribution gap of this species in the Brazilian Amazon and illustrates that the current knowledge on the distribution of Amazonian bats is far from complete.