Outcome of autologous hematopoietic stem cell transplantation in refractory multiple myeloma.

Veltri, Lauren W; Milton, Denái R.; Delgado, Ruby; Shah, Nina; Patel, Krina; Nieto, Yago; Kebriaei, Partow; Popat, Uday R; Parmar, Simrit; Oran, Betul; Ciurea, Stefan O.; Hosing, Chitra; Lee, Hans C; Manasanch, Elisabet; Orlowski, Robert Z.; Shpall, Elizabeth J.; Champlin, Richard E.; Qazilbash, Muzaffar H; Bashir, Qaiser

doi:10.1002/cncr.30770

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Outcome of autologous hematopoietic stem cell transplantation in refractory multiple myeloma.

Author(s): Lauren W Veltri ¹ , Denái R Milton ² , Ruby Delgado ¹ , Nina Shah ¹ , Krina Patel ¹ , Yago Nieto ¹ , Partow Kebriaei ¹ , Uday R Popat ¹ , Simrit Parmar ¹ , Betul Oran ¹ , Stefan Ciurea ¹ , Chitra Hosing ¹ , Hans C Lee ³ , Elisabet Manasanch ³ , Robert Z Orlowski ³ , Elizabeth J Shpall ¹ , Richard E Champlin ¹ , Muzaffar H Qazilbash ¹ , Qaiser Bashir ¹

Publication date (Electronic): May 17 2017

Journal: Cancer

Publisher: Wiley-Blackwell

Keywords: autologous transplantation, immunomodulatory agent, multiple myeloma, proteasome inhibitor, refractory disease

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Abstract

Despite the introduction of effective, novel agents, the outcome of patients with refractory multiple myeloma remains poor, particularly those who are refractory to both proteasome inhibitors (PIs) and immunomodulatory agents (IMiDs). Limited data are available on the role of autologous hematopoietic stem cell transplantation in this population.

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Journal ID (iso-abbrev): Cancer

Title: Cancer

Publisher: Wiley-Blackwell

ISSN (Electronic): 1097-0142

ISSN (Print): 0008-543X

Publication date (Electronic): May 17 2017

Affiliations

[1 ] Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.

[2 ] Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

[3 ] Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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DOI: 10.1002/cncr.30770

PubMed ID: 28513828

SO-VID: 44c7a158-e3a5-4454-bc49-ffe42153aa21

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Keywords: autologous transplantation,immunomodulatory agent,multiple myeloma,proteasome inhibitor,refractory disease

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Keywords: autologous transplantation, immunomodulatory agent, multiple myeloma, proteasome inhibitor, refractory disease

Outcome of autologous hematopoietic stem cell transplantation in refractory multiple myeloma.

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