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      Pharmacodynamic equivalence of a decapeptyl 3-month SR formulation with the 28-day SR formulation in patients with advanced prostate cancer.

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          Abstract

          The objective of the study was to assess the pharmacodynamic equivalence of LHRH analogue triptorelin 3-month and 28-day SR formulations.

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          Most cited references5

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          Gonadotropin-releasing hormone: one polypeptide regulates secretion of luteinizing and follicle-stimulating hormones.

          A polypeptide isolated from porcine hypothalami stimulates the release of both luteinizing hormone and follicle-stimulating hormone from the pituitaries of several species. This polypeptide has been structurally identified as (pyro)Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH(2) and synthesized. The natural and synthetic materials share biological properties. It appears that this peptide represents the hypothalamic hormone regulating the secretion of both luteinizing hormone and follicle-stimulating hormone.
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            Chapter 21. Luteinizing Hormone Releasing Hormone (LHRH) Analogues

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              Orchiectomy versus Long-acting D-Trp-6-LHRH in Advanced Prostatic Cancer

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                Author and article information

                Journal
                Horm. Res.
                Hormone research
                S. Karger AG
                0301-0163
                0301-0163
                2004
                : 62
                : 5
                Affiliations
                [1 ] Centre Hospitalier Universitaire Saint Louis, Paris, France. pierre.teillac@sls.ap-hop-paris.fr
                Article
                81629
                10.1159/000081629
                15499224
                e768e680-5765-410c-9cc9-cbce487a614a
                History

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