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      International Journal of COPD (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on pathophysiological processes underlying Chronic Obstructive Pulmonary Disease (COPD) interventions, patient focused education, and self-management protocols. Sign up for email alerts here.

      39,063 Monthly downloads/views I 2.893 Impact Factor I 5.2 CiteScore I 1.16 Source Normalized Impact per Paper (SNIP) I 0.804 Scimago Journal & Country Rank (SJR)

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      Influence of indacaterol on daily physical activity in patients with untreated chronic obstructive pulmonary disease.

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          Abstract

          Indacaterol, a once-daily, long-acting β2-agonist, may improve not only respiratory function, dyspnea symptoms, and quality of life, but also physical activity for patients with chronic obstructive pulmonary disease (COPD). This study aimed to evaluate the effect of 12-week indacaterol therapy on daytime physical activity in patients with untreated COPD.

          Most cited references19

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          Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study

          Christopher Murray, Alan Lopez (1997)
          The Lancet, 349(9064), 1498-1504
          Article 0 comments Cited 1148 times – based on 0 reviews     Review now
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            Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper.

            W MacNee, , B Celli (2004)
            Article 0 comments Cited 481 times – based on 0 reviews     Review now
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              Characteristics of physical activities in daily life in chronic obstructive pulmonary disease.

              Fabio Pitta, Thierry Troosters, Martijn Spruit … (2005)
              Quantification of physical activities in daily life in patients with chronic obstructive pulmonary disease has increasing clinical interest. However, detailed comparison with healthy subjects is not available. Furthermore, it is unknown whether time spent actively during daily life is related to lung function, muscle force, or maximal and functional exercise capacity. We assessed physical activities and movement intensity with the DynaPort activity monitor in 50 patients (age 64 +/- 7 years; FEV1 43 +/- 18% predicted) and 25 healthy elderly individuals (age 66 +/- 5 years). Patients showed lower walking time (44 +/- 26 vs. 81 +/- 26 minutes/day), standing time (191 +/- 99 vs. 295 +/- 109 minutes/day), and movement intensity during walking (1.8 +/- 0.3 vs. 2.4 +/- 0.5 m/second2; p < 0.0001 for all), as well as higher sitting time (374 +/- 139 vs. 306 +/- 108 minutes/day; p = 0.04) and lying time (87 +/- 97 vs. 29 +/- 33 minutes/day; p = 0.004). Walking time was highly correlated with the 6-minute walking test (r = 0.76, p < 0.0001) and more modestly to maximal exercise capacity, lung function, and muscle force (0.28 < r < 0.64, p < 0.05). Patients with chronic obstructive pulmonary disease are markedly inactive in daily life. Functional exercise capacity is the strongest correlate of physical activities in daily life.
              Article 0 comments Cited 277 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (iso-abbrev): Int J Chron Obstruct Pulmon Dis
                Title: International journal of chronic obstructive pulmonary disease
                Publisher: Informa UK Limited
                ISSN (Electronic): 1178-2005
                ISSN (Print): 1176-9106
                Publication date (Electronic): 2015
                Volume: 10
                Affiliations
                [1 ] Department of Respiratory Medicine, Osaka Police Hospital, Tennoji-ku, Osaka, Japan.
                [2 ] Department of Respiratory Medicine, Osaka Police Hospital, Tennoji-ku, Osaka, Japan ; Department of Internal Medicine, National Hospital Organization, Kinki-Chuo Chest Medical Center, Kita-ku, Sakai, Osaka, Japan.
                Article
                Publisher Item ID: copd-10-439
                DOI: 10.2147/COPD.S76836
                PMC ID: 4354394
                PubMed ID: 25767381
                SO-VID: 66efcc73-cd36-4dbe-b191-fc8ac9359e25
                History

                Keywords: chronic obstructive pulmonary disease,indacaterol,long-acting β2-agonist,physical activity,uniaxial accelerometer
                Data availability:
                Keywords: chronic obstructive pulmonary disease, indacaterol, long-acting β2-agonist, physical activity, uniaxial accelerometer

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