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      An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.

      The New England journal of medicine
      Massachusetts Medical Society

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          Abstract

          The relative efficacy of streptokinase and tissue plasminogen activator and the roles of intravenous as compared with subcutaneous heparin as adjunctive therapy in acute myocardial infarction are unresolved questions. The current trial was designed to compare new, aggressive thrombolytic strategies with standard thrombolytic regimens in the treatment of acute myocardial infarction. Our hypothesis was that newer thrombolytic strategies that produce earlier and sustained reperfusion would improve survival.

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          8204123
          10.1056/NEJM199309023291001

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