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      Minimap2: pairwise alignment for nucleotide sequences.

      1
      Bioinformatics (Oxford, England)
      Oxford University Press (OUP)

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          Abstract

          Recent advances in sequencing technologies promise ultra-long reads of ∼100 kb in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 Mb in length. Existing alignment programs are unable or inefficient to process such data at scale, which presses for the development of new alignment algorithms.

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          Author and article information

          Journal
          Bioinformatics
          Bioinformatics (Oxford, England)
          Oxford University Press (OUP)
          1367-4811
          1367-4803
          September 15 2018
          : 34
          : 18
          Affiliations
          [1 ] Department of Medical Population Genetics Program, Broad Institute, Cambridge, MA, USA.
          Article
          4994778
          10.1093/bioinformatics/bty191
          6137996
          29750242
          f3569d09-eed4-468a-af26-738e771f4f84
          History

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