Serological study ofNeospora caninuminfection in dogs in central China

Abstract

Neospora caninum is a protozoan parasite that causes abortion in cattle as well as reproduction problems and neurological disorders in dogs. Dogs are important in the epidemiology of N. caninum because they act as definitive hosts, shedding oocysts in the environment. To investigate the seroprevalence of N. caninum infection in dogs in central China, 1176 serum samples were collected from domestic dogs in Henan province, central China between March 2015 and February 2016 and tested for IgG antibody against N. caninum, using the indirect fluorescent antibody test (IFAT). The overall seroprevalence of N. caninum was nearly 15% (172/1176). No significant difference was observed between this seroprevalence according to sex and breed of dogs (p > 0.05). The infection rate in rural dogs (18%) was higher (p < 0.05) than in urban dogs (11%). The prevalence of N. caninum infection in dogs increased (p < 0.05) with age. The results of the present study indicate the high prevalence of N. caninum antibodies in dogs in Henan province, central China. Sanitary conditions and animal health must be improved to prevent the transmission risk of N. caninum by dogs.