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Bronchodilator effect of delta1-tetrahydrocannabinol.

Author(s): J. P. Hartley, S Nogrady, A. Seaton

Publication date: 1978-05-31

Journal: British Journal of Clinical Pharmacology

Keywords: Adult, Aged, Asthma, physiopathology, Bronchodilator Agents, Dronabinol, pharmacology, Female, Forced Expiratory Volume, Humans, Middle Aged, Peak Expiratory Flow Rate, Time Factors

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Abstract

1 delta1-trans-tetrahydrocannabinol, (delta1-THC) produces bronchodilatation in asthmatic patients. 2 Administered in 62 microliter metered volumes containing 50--200 microgram by inhalation from an aerosol device to patients judged to be in a steady state, it increased peak expiratory flow rate (PEFR) and forced expiratory volume in 1 second (FEV1). 3 The rate of onset, magnitude, and duration of the bronchodilator effect was dose related.

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PubMed ID:: 656294

PMC ID:: 1429361

ScienceOpen disciplines: Chemistry

Keywords: Adult,Aged,Asthma,physiopathology,Bronchodilator Agents,Dronabinol,pharmacology,Female,Forced Expiratory Volume,Humans,Middle Aged,Peak Expiratory Flow Rate,Time Factors

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ScienceOpen disciplines: Chemistry

Keywords: Adult, Aged, Asthma, physiopathology, Bronchodilator Agents, Dronabinol, pharmacology, Female, Forced Expiratory Volume, Humans, Middle Aged, Peak Expiratory Flow Rate, Time Factors

Bronchodilator effect of delta1-tetrahydrocannabinol.

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