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      Abnormalities in 3-Dimensional Left Ventricular Mechanics With Anthracycline Chemotherapy Are Associated With Systolic and Diastolic Dysfunction.

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          Abstract

          The objective of this study was to evaluate the changes in three-dimensional (3D) speckle-tracking echocardiography-derived measures of mechanics and their associations with systolic and diastolic dysfunction after anthracyclines.

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          Author and article information

          Journal
          JACC Cardiovasc Imaging
          JACC. Cardiovascular imaging
          Elsevier BV
          1876-7591
          1876-7591
          Aug 2018
          : 11
          : 8
          Affiliations
          [1 ] Division of Cardiology, Barnes-Jewish Hospital, St. Louis, Missouri.
          [2 ] Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
          [3 ] Division of Cardiology, Tufts Medical Center, Boston, Massachusetts.
          [4 ] Department of Pediatrics, Division of Cardiology, Rady Children's Hospital San Diego, The University of California-San Diego, San Diego, California.
          [5 ] Division of Hematology and Oncology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
          [6 ] Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
          [7 ] Division of Cardiology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
          [8 ] Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Center for Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. Electronic address: bonnie.ky@uphs.upenn.edu.
          Article
          S1936-878X(18)30122-0
          10.1016/j.jcmg.2018.01.015
          29550306
          f75a67f2-a263-4f0d-8084-3be5e166fdc7
          History

          anthracyclines,3D echocardiography,cardio-oncology
          anthracyclines, 3D echocardiography, cardio-oncology

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